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Coronavirus: Oxford vaccine triggers immune response

A coronavirus vaccine developed by the University of Oxford appears safe and triggers an immune response.
Trials involving 1,077 people showed the injection led to them making antibodies and T-cells that can fight coronavirus.
The findings are hugely promising, but it is still too soon to know if this is enough to offer protection and larger trials are under way.
The UK has already ordered 100 million doses of the vaccine.
The vaccine – called ChAdOx1 nCoV-19 – is being developed at unprecedented speed.
It is made from a genetically engineered virus that causes the common cold in chimpanzees.
It has been heavily modified, first so it cannot cause infections in people and also to make it “look” more like coronavirus.
Scientists did this by transferring the genetic instructions for the coronavirus’s “spike protein” – the crucial tool it uses to invade our cells – to the vaccine they were developing.
This means the vaccine resembles the coronavirus and the immune system can learn how to attack it.
Much of the focus on coronavirus so far has been about antibodies, but these are only one part of our immune defence.
Antibodies are small proteins made by the immune system that stick onto the surface of viruses.
Neutralising antibodies can disable the coronavirus.
T-cells, a type of white blood cell, help co-ordinate the immune system and are able to spot which of the body’s cells have been infected and destroy them.
Nearly all effective vaccines induce both an antibody and a T-cell response.
Levels of T-cells peaked 14 days after vaccination and antibody levels peaked after 28 days. The study has not run for long enough to understand how long they may last, the study in the Lancet showed.
Prof Andrew Pollard, from the Oxford research group told the BBC: “We’re really pleased with the results published today as we’re seeing both neutralising antibodies and T-cells.
“They’re extremely promising and we believe the type of response that may be associated with protection.
“But the key question everyone wants to know is does the vaccine work, does it offer protection… and we’re in a waiting game.”
The study showed 90% of people developed neutralising antibodies after one dose. Only ten people were given two doses and all of them produced neutralising antibodies.
“We don’t know the level needed for protection, but we can maximise responses with a second dose,” Prof Pollard told the BBC.
Yes, but there are side-effects.
There were no dangerous side-effects from taking the vaccine, however, 70% of people on the trial developed either fever or headache.
The researchers say this could be managed with paracetamol.

  • BBC
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Small-scale miners schooled on health hazards of mining with mercury

• Mr Lovelace Sarpong (right) addressing the participants

Mr Lovelace Sarpong (right) addressing the participants

Some Artisanal and Small-Scale Miners in the Ashanti and Central regions have been sensitised on the potential health dangers humans are exposed to with the use of mercu­ry in gold processing.

The sensitisation which was or­ganised by PlanetGOLD Ghana proj­ect was to raise awareness about the negative impacts on the use of mercury in mining activities.

According to the PlanetGOLD Ghana Project Coordinator, Mr Lovelace Sar­pong, the use of mercury in artisanal small-scale mining pose health challeng­es that affects the nervous, digestive and immune systems, lungs and kidneys; and may be fatal.

Some Metropolitan, Municipal, and District Assemblies (MMDAs) that benefited from the exercise were Amansie Central, Asante Akim North, Amansie South, Amansie West, Bekwai, and Adansi North in the Ashanti Region, and Upper Denkyira East (Dunkwa-on-Offin) and Upper Denkyira West (Diaso) in the Central Region.

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Additionally, he said inorganic salts of mercury were corrosive to the skin, eyes and gastrointestinal tract, and may induce kidney toxicity if ingested.

He stated that the PlanetGOLD Project has conducted several ini­tiatives to raise awareness on reducing mercury exposure among artisanal and small-scale gold mining actors in the country.

It was to promote mercury-free mining practices in line with Ghana’s obligations under the Minamata Con­vention on Mercury, support the for­malisation of the ASGM sector while advocating the adoption of the CRAFT Code and responsible supply chains, and raise awareness on the availabili­ty of mercury-free alternatives.

The Environmental Protection Agency (EPA) Area Head for Konongo, Mr Dawood Abbas, underscored the importance of government’s environ­mental regulations and EPA’s role in ensuring compliance within the ASGM sector.

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He encouraged miners to prioritise environmental stewardship to gain community trust and secure a Social License to Operate (SLO) and reaf­firmed the Agency’s commitment to enforce its commitments under the Minamata Convention.

 BY Cecilia Lagba Yada

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Stonebwoy releases sixth studio album ‘Up & Running’

Ghanaian multiple award-winning musician, Stonebwoy is out with his sixth studio album dubbed ‘Up & Running.’

As part of the release Stonebwoy performed various songs on the album to patrons at a special listening party last night.

The listening party held at the Alora Beach in Accra brought together Industry players, musicians, actors, corporate Ghana, diplomats and fans of Stonebwoy among others.

The album is made up of songs like, Memories, Pray For Me, Jejereje, Overload remix, Shine, Psalm 23, Betta Tin, Your Body, Geography, Shine, Lovely Weather, Jiggle and White, Ekelebe and Fvck Up Summer.

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 ‘Up & Running’ features the top musicians such as Duncan Mighty, Ir Sais, Spice, Amaria BB, Jahmiel, 10TIK, Larruso, Chi Ching Ching, Kaylan Arnold, and Blvk H3ro, Wyclef Jean and ODUMODUBLVCK.

The album, which includes diverse songs for different target markets, shows Stonebwoy’s calculated effort to reach out to wider and new audiences around the world.

Stonebwoy is expected to hit the road in a global tour with his new album, ‘Up & Running.’

The colourful event was attended by industry personalities like Fred Nuamah, Andy Dosty, Keche, Bullgod, Nadia Buari, Nana McBrown,Kwaw Kese,Robert Klah,D-Black, Larusso and many others.

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By Edem Mensah-Tsotorme

Enjoy the album below

UP & RUNNIN6 – ALBUM OUT NOW! ♨️

stonebwoy.lnk.to/UXR6

#UPXRUNNIN6 #UPXRUNNIN6Album

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