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Malaria pill trialed to prevent COVID-19

A trial to see whether two anti-malarial drugs could prevent COVID-19 has begun in Brighton and Oxford.
Chloroquine, hydroxychloroquine or a placebo will be given to more than 40,000 healthcare workers from Europe, Africa, Asia and South America.
All the participants are staff who are in contact with COVID-19 patients.
US President Donald Trump was criticised this week after he said he had been taking hydroxychloroquine, despite warnings it might be unsafe.
The first UK participants in the global trial were enrolled yesterday at the Brighton and Sussex University Hospitals and the John Radcliffe Hospital in Oxford.
They will be given either hydroxychloroquine or a placebo for three months. At sites in Asia, participants will be given chloroquine or a placebo.
These are the first of a planned 25 UK sites, with results expected by the end of the year.
The trial is open to anyone delivering direct care to coronavirus patients in the UK, as long as they have not been diagnosed with COVID-19.
It will test whether the drugs can prevent healthcare workers exposed to the virus from contracting it.
One of the study’s leaders, Prof Nicholas White at the University of Oxford said: “We really do not know if chloroquine or hydroxychloroquine are beneficial or harmful against COVID-19.”
But, he said, a randomised controlled trial such as this one, where neither the participant nor the researchers know who has been given the drug or a placebo, was the best way to find out.
“A widely available, safe and effective vaccine may be a long way off,” said Prof Martin Llewelyn from Brighton and Sussex Medical School, who is also leading the study.
“If drugs as well-tolerated as chloroquine and hydroxychloroquine could reduce the chances of catching COVID-19, this would be incredibly valuable.”
The drugs can reduce fever and inflammation and are used as both a prevention and a treatment for malaria.
Hydroxychloroquine regulates the body’s immune response and is also used in the treatment of rheumatoid arthritis and Lupus – an inflammatory disease caused by an overactive immune system.
Lupus charities in the UK and US have raised concerns that demand for the drug associated with coronavirus could threaten the supply for patients who already rely on it. -BBC
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GBBF assistant treasurer, Aurora Commodore-Toppar eyes GOC Treasure slot at Elective Congress on Saturday

The Assistant treasurer of the Ghana Basketball Federation (GBBF), Madam Aurora Commodore-Toppar, has set her sights on becoming the next assistant treasurer of the Ghana Olympic Committee (GOC) at the upcoming Elective Congress on Saturday.
The daughter of the former Chief Executive Officer of Accra Hearts of Oak, Mr. Emmanuel Martey Commodore-Mensah, will be vying for the position against Bernard Quartey of the Ghana Boxing Federation and Edward Patrick Nii Lante Banerman of the Handball Association of Ghana.
Having had her nomination approved by the GOC’s Electoral Commission, the well-seasoned banker, with over 15 years of rich working experience, believes she is well-suited and positioned to help structure the finances of this esteemed organisation.
In a chat with Spectator Sports, the captain of the bronze-winning 2024 University of Ghana basketball team at the 11th African University Games in Zaire, Nigeria, revealed her commitment to effective and accurate financial management, growth, and development of all associated sports federations.
She said, “I am committed to the growth of the GOC, and I want to offer my financial knowledge to aid in ensuring that the GOC operates with the highest standards of financial governance and set-up.”
According to her, the mission is to help promote the GOC’s agenda widely, and having served for over two decades in sports—especially basketball—in various capacities and roles, she believes this experience will help protect the GOC’s finances.
“If elected as assistant treasurer, I will do my utmost, together with the treasurer, to manage the GOC’s finances, including accounting and financial reporting among others,” she added.
According to her, “Accurate financial record-keeping has been a problem across the board; I will help eradicate this issue.”
Aurora Commodore-Toppar stands for transparency, hard work, and an inclusive work culture, she further added.
The former Aburi Girls’ Secondary School basketball team captain has played pivotal roles in improving sports in the country—especially basketball—including being a member of the Local Organizing Committee (LOC) for the 2023 Africa Games, an LOC member for the recently concluded Hoop Rave SHS competition, a project lead for FIBA’s “Her World, Her Rules” initiative, chair for the 2024 Fetu Afahye Basketball Tournament, and founder of the Stomp De Yard Basketball Tournament, among others.
BY RAYMOND ACKUMEY
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113 Cardinals hold 3rd General Congregation in Rome

The 113 Cardinals present in Rome held the third General Congregation on Thursday morning, and announced who will deliver the two pre-conclave meditations.
The Cardinals decided that Cardinal Víctor Manuel Fernández will celebrate the Mass on the sixth day of the Novemdiales, instead of Cardinal Kevin Farrell.
They agreed that Fr. Donato Ogliari, O.S.B., Abbot of St. Paul Outside the Walls, will deliver the first meditation on Monday, and that Cardinal Raniero Cantalamessa, Preacher Emeritus of the Papal Household, will deliver the second meditation at the beginning of the conclave, whose starting date has not yet been decided.
The Cardinals began a conversation about the Church and the world, deciding to hold the next General Congregation on Friday morning at 9:00 AM.
The Director of the Holy See Press Office, Matteo Bruni, told journalists that 61,000 people have paid their respects to the late Pope Francis as of 1:00 PM on Thursday, adding that St. Peter’s Basilica should close at midnight on Thursday, unless large crowds are still queuing to enter.
Following the Pope’s funeral on Saturday, April 26, a Rosary will be held in front of the Basilica of St. Mary Major on Saturday at 9:00 PM.
Mr. Bruni said the burial service for Pope Francis will take place in private.
Starting the morning of Sunday, April 27, the faithful may begin to visit the tomb of Pope Francis at the Marian Basilica.