Features
Coronavirus – Are the Numbers of Cases Reliable?
Right now, we are being told that the novel coronavirus that causes the Covid-19 disease is such an existential threat to all of us that we need extreme measures to deal with it. More than half the world’s population is bunkered down at home under effective house arrest; a form of medical martial law prevails of the streets; most “nonessential” shops and businesses are closed; and trust and social contact between people has almost completely broken down. So is the threat from the new disease worthy of these unprecedented consequences?
Let’s take a close look at the figures. A good source of official data which is updated regularly is the Worldometers Coronavirus page.. The latest figures here as of the time of writing (25th April 2020) are shown by the following summary snapshot from the site:
So, at this time we have more than two and a quarter million cases and more than 150,000 deaths. That sounds pretty bad, right? But we can only put this into context if we compare with the numbers for deaths and cases from other, broadly similar diseases and, for deaths, by comparing with global death rates as a whole.
I will return to the subject of death rates later, but firstly let’s concentrate on case numbers: how are these numbers being calculated? We hear a lot about testing of suspected cases, but what do we know about these tests?
The first thing to note is that, perhaps contrary to popular belief, there is not one standard test being used around the world to test for coronavirus infection; each country is more or less using its own methodology.
Also, as I have discussed in a previous post, tests are not a magic 100% reliable indicator of whether someone has a disease or not. Some of them are really quite unreliable indeed. It’s actually quite a technical challenge to make accurate tests for common diseases, particular those caused by viruses. If it were that easy, the shops would be full of such test kits. Do you not think there would be a huge market for a simple, accurate home test for, say, the flu? And the market would undoubtedly be much bigger for home tests for embarrassing viral diseases such as herpes and sexually transmitted infections.
And even if it were possible to manufacture a fairly accurate test for a disease, if the disease you are testing for is uncommon (as is currently the case with Covid-19 despite all the media hype to the contrary) then the rate of false positives this test will give you will be really high. I will go into more detail on this later to illustrate that the world is largely suffering from a pandemic of false positives for Covid-19 rather than of the disease itself.
The general approach to testing for Covid-19 can be gauged from the US Centre for Disease Control’s (CDC’s) web pages on testing and their information for laboratories doing Covid-19 testing. So, let’s take a look at the two main types of testing that are being done for Covid-19 around the world right now: polymerase chain reaction (PCR) based tests and serology/antibody-based tests.
PCR Based Tests
Many SARS-CoV-2 tests are based on what is called “Reverse Transcription Polymerase Chain Reaction” or RT-PCR. This is a type of more general process called the polymerase chain reaction (PCR). Wikipedia gives good general explanations of the principles of PCR testing as a whole, as well as the type of RT-PCR tests used for Covid-19 testing.
Without going into too many technical details here, the general idea of a PCR test is to take a sample from a patient and multiply up all the target DNA in the sample (using the polymerase chain reaction, PCR). The target DNA sequence used is designed to try and uniquely identify the target virus or bacteria so that if this sequence is found you can be reasonably sure you have found the target organism.
Serology/Antibody Based Tests
Given all the problems with PCR based testing, some companies and countries are investigating the use of antibody-based tests instead. The idea here is to try and detect antibodies – proteins produced by the body to fight infection – against the SARS-CoV-2 virus in the blood or other bodily fluids of a patient. The UK is working on getting antibody tests available in bulk for their population. The CDC in the US is also looking at developing such tests.
I won’t discuss these kinds of tests in so much detail because most countries including our own Ghana and health care systems are still mainly reliant on RT-PCR based testing. This is partly because accurate antibody tests are not widely available, being both difficult and time consuming to prepare in great numbers. But suffice to say that antibody tests, even when they have been successfully manufactured, are also subject to many problems too.
BY RISK OFORIWAA DAUDA
Features
Who knows tomorrow?
Recently a friend posted a sad news on his Facebook page, announcing the death of a school mate who had passed away, suddenly. The report had it that he was on his way to the airport to take a flight to Ghana.
I am sure this man had already informed the wife or a friend or a work colleague at work that he was returning home but he was not to return as a human being but as a dead body.
Such is life and so we need to be circumspect in how we go about things in life. The Bible reminds us that we are like grass which at one point in time looks elegant and the next moment becomes withered according to Psalm 90:5 and 6. It is for this reason that we need to guard our hearts with the word of God so that we shall be motivated to do the right thing, at all times.
This will enable us live on this planet, free from all sorts of troubles in our personal lives, even if we ignore the question of Heaven and Hell. Living a disciplined life delivers us from any kind of trouble as the Bible declares in Galatians 5:23 that against such there is no law.
The uncertainty surrounding our lives on earth is the more reason why people should commit their lives into the hands of the one who created it, in the first place unless you believe that the world created itself and that it appeared from nowhere.
Otherwise, the logical thing to do is to recognize the authority of the creator and surrender to his Lordship. Heaven is real and Hell is real, so for us who know the truth and have received Jesus as our Lord and Saviour, the onus lies on us to encourage our relations who have not believed and received Jesus into their lives, to do so.
We are a couple of days from another Easter Resurrection celebration and an opportunity to reflect on our lives in relation to the significance of Easter. In the Bible, the only occasion Jesus, Saviour of the world commands us to celebrate is his death and resurrection.
He never commanded his followers to celebrate his birth but like everything else, we chose to ignore Jesus’s instructions and decided to do what pleases us, just like our forefather and mother in the Garden of Eden.
Let us deliberately choose to do things differently as Christians this Easter, so we can really benefit from all the blessings that the celebration of the death and birth of Jesus, has on offer. Doing the same thing over and over and expecting a different result is definitely insanity.
I choose to be different this Easter and I am believing God for a newness of life so God’s glory would be revealed in me to draw the unsaved to him. It is only when people especially the unsaved, see the character of Christ in us, that they can be convinced about the authenticity of Jesus, as Saviour of the world, who can bring transformation in their lives too.
This is what would motivate them to surrender their lives to Jesus Christ. Let us make this Easter a memorable one that will be cherished for a long time. It is also a period for reconciliation and it would be great if in the spirit of Easter, we would try to reach out to those who have wronged us or have a grudge against us.
This would demonstrate that we have indeed accepted Jesus and that our religious posture is not a sham. May the good Lord grant us the grace to love our neighbours as ourselves, demonstrating the love of God in the process.
Those who have lost their loved ones and Easter brings sad memories, may the good Lord comfort and strengthen you. God bless.
.NB: ‘CHANGE KOTOKA INTERNATIONAL AIRPORT TO KOFI BAAKO INTERNATIONAL AIRPORT’
Features
Cosmetic deformities
COSMETIC deformities refer to physical imperfections or abnormalities that affect an individual’s appearance, often causing emotional distress and impacting their quality of life.
These deformities can be congenital, acquired, or result from various medical conditions or treatments. This article provides an in-depth exploration of cosmetic deformities, their types, causes, effects, and treatment options.
Types of cosmetic deformities
Cosmetic deformities can affect various parts of the body, including the face, skin, hair, nails, and teeth. Some common types of cosmetic deformities include:
1. Facial deformities: Congenital or acquired abnormalities affecting the shape, structure, or appearance of the face, such as cleft lip and palate, facial paralysis, or facial asymmetry.
2. Skin deformities: Conditions affecting the skin’s texture, tone, or appearance, such as acne, scars, birthmarks, or skin discoloration.
3. Hair deformities: Abnormalities affecting the hair’s growth, texture, or appearance, such as alopecia, hirsutism, or hair loss due to medical conditions or treatments.
4. Nail deformities: Conditions affecting the shape, size, or appearance of the nails, such as nail fungus, nail psoriasis, or nail trauma.
5. Dental deformities: Abnormalities affecting the shape, size, or appearance of the teeth, such as tooth decay, tooth loss, or malocclusion.
Causes of cosmetic deformities
Cosmetic deformities can result from various factors, including:
1. Genetics: Congenital conditions or inherited traits can cause cosmetic deformities.
2. Trauma: Injuries or accidents can result in cosmetic deformities, such as scars or facial trauma.
3. Medical conditions: Certain medical conditions, such as acne, psoriasis, or eczema, can cause cosmetic deformities.
4. Treatments and procedures: Medical treatments, such as chemotherapy, radiation therapy, or surgery, can result in cosmetic deformities.
5. Aging and environmental factors: Aging, sun exposure, and environmental factors can contribute to cosmetic deformities, such as wrinkles, fine lines, or age spots.
Effects of cosmetic deformities
Cosmetic deformities can have significant emotional and psychological effects on individuals, including:
1. Low self-esteem: Cosmetic deformities can lead to feelings of insecurity, self-consciousness, and low self-esteem.
2. Social anxiety: Individuals with cosmetic deformities may experience social anxiety, avoiding social interactions or feeling embarrassed in public.
3. Emotional distress: Cosmetic deformities can cause emotional distress, including depression, anxiety, or stress.
4. Impact on quality of life: Cosmetic deformities can affect an individual’s quality of life, impacting their relationships, career, or overall well-being.
Treatment options for cosmetic deformities
Various treatment options are available to address cosmetic deformities, including:
1. Surgical procedures: Surgical procedures, such as reconstructive surgery, cosmetic surgery, or dermatological surgery, can correct or improve cosmetic deformities.
2. Non-surgical treatments: Non-surgical treatments, such as laser therapy, chemical peels, or microdermabrasion, can address cosmetic concerns, such as skin texture, tone, or appearance.
3. Medical treatments: Medical treatments, such as topical creams, oral medications, or injectable treatments, can address cosmetic concerns, such as acne, hair loss, or nail deformities.
4. Prosthetic and orthotic devices: Prosthetic and orthotic devices, such as wigs, hairpieces, or dental prosthetics, can help individuals with cosmetic deformities.
5. Counselling and therapy: Counselling and therapy, such as cognitive-behavioral therapy or psychotherapy, can help individuals cope with the emotional and psychological effects of cosmetic deformities.
Conclusion
Cosmetic deformities can have significant emotional and psychological effects on individuals, impacting their quality of life and overall well-being.
Understanding the types, causes, and effects of cosmetic deformities is crucial in addressing these concerns.
Various treatment options are available, ranging from surgical procedures to non-surgical treatments, medical treatments, prosthetic and orthotic devices, and counselling and therapy.
By seeking professional help and support, individuals with cosmetic deformities can improve their appearance, boost their self-esteem, and enhance their overall quality of life.
Reference
1. “Cosmetic Deformities” by the American Society of Plastic Surgeons
